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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
38.79
Human Site:
Y379
Identified Species:
53.33
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
Y379
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
M
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
Y379
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
M
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
G500
R
I
H
Q
S
T
Y
G
K
S
L
A
I
M
T
Dog
Lupus familis
XP_543550
1017
111618
Y379
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
M
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
Y379
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
M
Rat
Rattus norvegicus
NP_001129232
1015
111665
Y379
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
Y379
S
N
I
H
Q
S
T
Y
G
K
S
L
A
I
M
Frog
Xenopus laevis
Q8QFR2
1013
112021
Y379
N
N
I
H
Q
S
T
Y
G
K
S
L
A
I
T
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
Y379
N
A
I
H
Q
N
I
Y
G
K
S
L
A
I
T
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
Y379
N
S
I
H
Q
N
I
Y
G
K
S
L
A
I
T
Fruit Fly
Dros. melanogaster
O17468
1047
113397
Y376
N
A
I
I
R
K
M
Y
G
K
N
Y
V
N
G
Honey Bee
Apis mellifera
XP_001122939
838
91355
S225
T
T
H
V
L
R
L
S
W
S
P
D
G
Q
Y
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
I322
T
L
K
P
L
F
V
I
N
N
I
F
N
H
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
S351
S
W
S
P
D
G
Y
S
L
F
A
C
S
L
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
Y379
D
E
L
K
K
S
R
Y
G
D
V
R
G
R
Q
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
K227
H
I
I
T
E
P
F
K
E
S
P
L
T
T
Y
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
E377
A
A
Q
F
E
T
G
E
L
G
W
V
A
K
S
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
93.3
80
66.6
66.6
26.6
0
0
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
80
80
46.6
6.6
6.6
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
20
13.3
6.6
P-Site Similarity:
N.A.
26.6
N.A.
33.3
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
18
0
0
0
0
0
0
0
0
6
6
59
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% C
% Asp:
6
0
0
0
6
0
0
0
0
6
0
6
0
0
6
% D
% Glu:
0
6
0
0
12
0
0
6
6
0
0
0
0
0
0
% E
% Phe:
0
0
0
6
0
6
6
0
0
6
0
6
0
0
0
% F
% Gly:
0
0
0
0
0
6
6
6
65
6
0
0
12
0
6
% G
% His:
6
0
12
53
0
0
0
0
0
0
0
0
0
6
0
% H
% Ile:
0
12
65
6
0
0
12
6
0
0
6
0
6
53
0
% I
% Lys:
0
0
6
6
6
6
0
6
6
59
0
0
0
6
0
% K
% Leu:
0
6
6
0
12
0
6
0
12
0
6
59
0
6
0
% L
% Met:
0
0
0
0
0
0
6
0
0
0
0
0
0
6
36
% M
% Asn:
24
12
0
0
0
12
0
0
6
6
6
0
6
6
0
% N
% Pro:
0
0
0
12
0
6
0
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
6
6
53
0
0
0
0
0
0
0
0
6
6
% Q
% Arg:
6
30
0
0
6
6
6
0
0
0
0
6
0
6
0
% R
% Ser:
42
6
6
0
6
48
0
12
0
18
53
0
6
0
6
% S
% Thr:
12
6
0
6
0
12
42
0
0
0
0
0
6
6
30
% T
% Val:
0
0
0
6
0
0
6
0
0
0
6
6
6
0
0
% V
% Trp:
0
6
0
0
0
0
0
0
6
0
6
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
65
0
0
0
6
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _